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Sitagliptin: Type 1 diabetes mellitus, diabetic ketoacidosis. Patients who are hypersensitive to Sitagliptin or to any components of the product.
Metformin Hydrochloride: Diabetic coma, ketoacidosis, impaired renal function, chronic liver disease, cardiac failure, recent myocardial infarction, alcoholism, tissue hypoxia, lactic acidosis, severe infections, trauma, surgery, dehydration.
